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platelet-rich plasma (Obafemi Awolowo University Teaching Hospitals Complex)
- Development stage
- Unknown
- Lead developer
- Obafemi Awolowo University Teaching Hospitals Complex
- Modality
- Cell Therapies
- Administration
- Intralesional
01
Overview
Platelet-rich plasma (PRP) is an autologous biological therapy prepared by concentrating platelets from a patient's own peripheral blood. Upon activation, these platelets release a variety of growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF), which facilitate tissue repair and modulate inflammatory processes. In a Phase 3 clinical trial led by the Obafemi Awolowo University Teaching Hospital, PRP is being evaluated as an intralesional injection for the treatment of early-stage trigger finger disorder (stenosing tenosynovitis) in Black adults, aiming to provide a regenerative alternative to the current standard of care, corticosteroid injections like Depo-Medrol.
- Other names
- PRPautologous platelet-rich plasma
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