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platelet-rich plasma (South Egypt Cancer Institute)
- Development stage
- Unknown
- Lead developer
- South Egypt Cancer Institute
- Modality
- Cell Therapies
- Administration
- Perineural
01
Overview
Platelet-rich plasma (PRP) is an autologous blood product characterized by a platelet concentration significantly higher than the baseline in whole blood. It contains a diverse array of growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF), which are released upon platelet activation. These factors promote tissue healing, angiogenesis, and neuroprotection. In the treatment of chemotherapy-induced peripheral neuropathy (CIPN), PRP is administered via ultrasound-guided perineural injection to target damaged nerves, aiming to reduce neuropathic pain and improve functional recovery through its regenerative and anti-inflammatory properties. The South Egypt Cancer Institute is investigating this therapy in clinical trials for cancer patients suffering from CIPN.
- Other names
- PRPautologous platelet-rich plasma
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