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platelet-rich plasma (University of the Basque Country)
- Development stage
- Unknown
- Lead developer
- University of the Basque Country
- Administration
- Intramuscular
01
Overview
Platelet-rich plasma (PRP) is an autologous biological therapy being investigated by the University of the Basque Country (UPV/EHU) for the treatment of acute muscle injuries, specifically in professional football players. The therapy involves concentrating a patient's own platelets, which, upon activation, release a variety of growth factors and bioactive molecules (such as PDGF, TGF-β, and VEGF) that facilitate muscle tissue regeneration and repair. In the clinical trial NCT03676205, the PRP is prepared using the Ortho pras® system and administered via ultrasound-guided intramuscular injections. The study aims to evaluate whether PRP reduces the time to return to play and decreases injury recurrence compared to homeopathic treatments.
- Brand names
- Ortho pras
- Other names
- PRPautologous platelet-rich plasma
02
Targets
TGFBR1/TGFBR2 (Transforming growth factor-beta receptor type 1 / Transforming growth factor-beta receptor type 2)PDGFRA (Platelet-derived growth factor receptor alpha)IGF-1R (Insulin-like growth factor 1 receptor)FGFR (Fibroblast growth factor receptor)VEGFR2 (Vascular endothelial growth factor receptor 2)
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