plectranthus amboinicus extract + centella asiatica extract

This is a combination of **Plectranthus amboinicus extract** and **Centella asiatica extract**, both plant-derived ingredients used in herbal and cosmetic preparations. **Plectranthus amboinicus extract** (Indian borage, also called Cuban oregano) contains bioactive compounds with antioxidant, anti-inflammatory, antimicrobial, and wound-healing properties. It reduces pro-inflammatory cytokines (e.g., TNF-α, IL-1β, IL-6), increases the anti-inflammatory cytokine IL-10, and demonstrates broad-spectrum antimicrobial activity. Primary mechanisms involve inhibition of inflammatory mediators and support of skin barrier recovery. **Centella asiatica extract** is widely used for its wound-healing, anti-inflammatory, antioxidant, and collagen-stimulating properties, primarily attributed to triterpenoids such as asiaticoside and madecassoside. The extract promotes fibroblast proliferation, extracellular matrix synthesis, and inhibits inflammatory pathways. This combination is found in topical formulations targeting skin barrier repair, anti-inflammatory effects, wound healing, and general skin health in both cosmetic and medicinal contexts.