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PLEL gel
- Development stage
- Preclinical
- Lead developer
- custom polymer manufacturers
- Modality
- Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Injectable, Topical, Implant, Subcutaneous, Intratumoral, Intralesional
01
Overview
PLEL gel refers to a thermosensitive hydrogel composed of poly(L-lactide-co-ethylene glycol-co-L-lactide), commonly abbreviated as PLEL. This material is a synthetic copolymer that forms a sol at low temperatures and transitions into a gel at body temperature. It is primarily used as an injectable or topical drug delivery system, enabling sustained and localized release of various therapeutic agents (such as chemotherapeutics, antibiotics, or proteins). The mechanism of action depends on the active ingredient loaded into the hydrogel; the polymer itself acts as an inert carrier matrix. The main application for PLEL gels has been in experimental settings for controlled drug delivery in oncology, wound healing, and tissue engineering.
- Brand names
- PLEL gel
- Other names
- PLEL hydrogelpoly(L-lactide-co-ethylene glycol-co-L-lactide) hydrogel
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