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Plenum Osshp + injectable platelet-rich fibrin
- Development stage
- Unknown
- Lead developer
- Plenum
- Administration
- Injectable
01
Overview
Plenum Osshp + injectable platelet-rich fibrin is a combination therapy used primarily in regenerative and oral-maxillofacial medicine, notably in bone grafting and sinus elevation procedures[1]. Plenum Osshp is a synthetic or xenogenic bone substitute (details on composition not available in search results) employed as a scaffold to support bone regeneration. Injectable platelet-rich fibrin (i-PRF) is an autologous blood-derived biomaterial made from the patient's own blood, spun to yield a concentrated fraction rich in platelets, leukocytes, cytokines, and growth factors embedded within a fibrin matrix[3][6]. This combination enhances healing by both providing a scaffold (Plenum Osshp) and delivering a sustained release of growth factors and pro-regenerative cytokines (i-PRF)[1][6]. The i-PRF component acts by stimulating angiogenesis, tissue regeneration, reducing inflammation, and supporting stem cell recruitment and differentiation[3][5][6]. This combination is being investigated for accelerating bone and soft tissue regeneration and reducing healing times in surgeries such as maxillary sinus augmentation[1].
- Brand names
- Plenum Osshp + i-PRF
- Other names
- injectable platelet-rich fibrini-PRFi-PR
02
Targets
ERBB2 (Erb-b2 receptor tyrosine kinase 2)IGF-1R (Insulin-like growth factor 1 receptor)PDGFRA (Platelet-derived growth factor receptor alpha)TGFBR (TGF-beta receptor)VEGFR (VEGFR family)PDGF (Platelet-derived Growth Factor family)TGFB (GARP–latent transforming growth factor beta 1 complex)VEGFA (Vascular endothelial growth factor A)
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