Plenum Osshp + injectable platelet-rich fibrin

Plenum Osshp + injectable platelet-rich fibrin is a combination therapy used primarily in regenerative and oral-maxillofacial medicine, notably in bone grafting and sinus elevation procedures[1]. Plenum Osshp is a synthetic or xenogenic bone substitute (details on composition not available in search results) employed as a scaffold to support bone regeneration. Injectable platelet-rich fibrin (i-PRF) is an autologous blood-derived biomaterial made from the patient's own blood, spun to yield a concentrated fraction rich in platelets, leukocytes, cytokines, and growth factors embedded within a fibrin matrix[3][6]. This combination enhances healing by both providing a scaffold (Plenum Osshp) and delivering a sustained release of growth factors and pro-regenerative cytokines (i-PRF)[1][6]. The i-PRF component acts by stimulating angiogenesis, tissue regeneration, reducing inflammation, and supporting stem cell recruitment and differentiation[3][5][6]. This combination is being investigated for accelerating bone and soft tissue regeneration and reducing healing times in surgeries such as maxillary sinus augmentation[1].

Brand names

Plenum Osshp + i-PRF

Other names

injectable platelet-rich fibrini-PRFi-PR