Drug intelligence / Profile preview

PlexoZome Levagen

Development stage
Unknown
Lead developer
Pharmako Biotechnologies
Modality
Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical
01

Overview

PlexoZome Levagen is a **topical spray formulation containing palmitoylethanolamide (PEA) delivered via liposomal technology** (PlexoZome®), designed for enhanced bioavailability and targeted delivery[4][5][2][7]. PEA is an endogenous fatty acid amide with scientifically established **anti-inflammatory, analgesic, and immune-modulating effects**[5][3][7]. The liposomal PlexoZome technology provides genuine, customizable liposome encapsulation for PEA to increase stability, skin penetration, and efficacy[4][2]. The primary indication is for **relief of joint and muscle pain, including post-exercise knee pain and arthritis**[1][5][7]. Clinical trials show the spray achieves faster and more effective pain reduction versus placebo, with no significant adverse effects reported[5][7]. Developed and manufactured in Australia, the product benefits from advanced delivery system research[6].

Brand names
PlexoZome Levagen
Other names
PlexoZome LevagenPlexoZomeLevagenLevagen+palmitoylethanolamide liposomal spray
02

Targets

CNR2 (Cannabinoid receptor type 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)FAAHPPARA (Peroxisome proliferator-activated receptor alpha)GPR55 (G protein-coupled receptor 55)

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