Drug intelligence / Profile preview

Plexus

Development stage
Unknown
Lead developer
Laboratorios Bagó
Modality
Small Molecules
Administration
Oral
01

Overview

Plexus is a combination pharmaceutical product containing the mucolytic agent **ambroxol** and the first-generation antihistamine **dexchlorpheniramine maleate**. Ambroxol facilitates respiratory tract clearance by reducing mucus viscosity and stimulating surfactant production; it also exhibits local anesthetic properties through the inhibition of voltage-gated sodium channels. Dexchlorpheniramine maleate serves as a competitive antagonist at H1 histamine receptors, effectively reducing allergic symptoms such as edema, pruritus, and secretions. This combination is primarily utilized in international markets for the symptomatic treatment of respiratory conditions where both airway congestion and allergic triggers are present, such as allergic bronchitis or rhinobronchitis.

Brand names
Plexus
Other names
ambroxol + dexchlorpheniramine
02

Targets

HRH1 (Histamine H1 Receptor)

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