Drug intelligence / Profile preview

PLGAI-004

Development stage
Unknown
Lead developer
Peptilogics
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules, Peptides
01

Overview

PLGAI-004 is a synthetic peptide-based therapeutic under development by Peptilogics for the treatment of cancer (neoplasms). It is classified as an antineoplastic agent and represents a new molecular entity. The drug is being developed using Peptilogics' AI-driven platform, Nautilus. As of the latest updates in early 2025, its mechanism of action remains undefined or undisclosed. The compound has not received orphan drug status and is currently in the discovery or early research phase with no clinical trial data reported[1][2][7].

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