Drug intelligence / Profile preview

PLpro protease inhibitor

Development stage
Preclinical
Lead developer
Sunshine Biopharma
Modality
Small Molecules
Administration
Oral
01

Overview

PLpro protease inhibitor is a small molecule drug candidate developed by Sunshine Biopharma under an exclusive worldwide royalty-bearing license agreement with the University of Arizona. It is designed to target SARS Coronavirus infections, including SARS-CoV-2, SARS-CoV, and MERS-CoV, by inhibiting the PLpro protease enzyme. The drug candidate is currently in preclinical development and has demonstrated efficacy in mouse models.

02

Targets

PLpro (Papain-like protease)

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