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PluroGel PN
- Development stage
- Unknown
- Lead developer
- Medline Industries
- Modality
- Small Molecules, Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
PluroGel PN is a topical antibiotic wound dressing developed by PluroGen Therapeutics for the treatment of mildly infected diabetic foot ulcers. The product utilizes a unique combination of antibiotics (typically polymyxin B and neomycin) incorporated into the proprietary PluroGel platform, which is a concentrated, surfactant-based, water-soluble hydrogel. This platform is designed to maintain a moist wound healing environment while providing wound cleaning, hydration, and debriding properties. PluroGel PN has been evaluated in Phase 2 clinical trials (PGN-1300 and PGN-1300X) in the United States, aiming to address the significant unmet need for an FDA-approved topical antibiotic specifically indicated for infections in diabetic foot ulcers.
- Brand names
- PluroGel PN
- Other names
- PluroGel PN Topical Antibiotic
02
Targets
Bacterial Ribosome
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