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PM1015 is a monoclonal antibody that specifically targets CD73 (ecto-5'-nucleotidase), functioning as a CD73 inhibitor. By inhibiting CD73, which plays a role in the production of immunosuppressive adenosine in the tumor microenvironment, PM1015 aims to enhance anti-tumor immune responses. The drug is being developed primarily for the treatment of advanced solid tumors and liver cancer. It is currently undergoing phase 1 clinical trials to evaluate its safety, pharmacokinetics, and preliminary efficacy in patients with advanced malignant solid neoplasms[1][2][3][5]. The developer and active organization for this drug is Biotheus.
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