Drug intelligence / Profile preview

pneumococcal 13-valent conjugate vaccine (Nivad Pharmed Salamat)

Development stage
Approved
Lead developer
Pfizer
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Pneumovax 13 is an incorrect name or misnomer that conflates Merck's 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23) and Pfizer's 13-valent pneumococcal conjugate vaccine (Prevnar 13), or refers to PneumoConj 13, a 13-valent pneumococcal conjugate vaccine developed by NIVAD Pharmed Salamat. PneumoConj 13 consists of pneumococcal capsular polysaccharides from 13 Streptococcus pneumoniae serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F) individually conjugated to a non-toxic diphtheria toxin mutant carrier protein (CRM197). It is designed to active immune responses for the prevention of invasive pneumococcal diseases, such as pneumonia, meningitis, and bacteremia, particularly in infants and children.

Brand names
PneumoConj 13PneumoConj13PneumoConj-13Pneumovax 13Pneumovax13Pneumovax-13
Other names
PCV13PCV-13PCV 13pneumococcal 13-valent conjugate vaccinepneumococcal13-valent conjugate vaccinepneumococcal-13-valent conjugate vaccinepneumococcal conjugate vaccine 13-valent
02

Targets

TCR-CRM197 (CRM197-specific T-cell receptor)CPS (Streptococcus pneumoniae capsular polysaccharide)BCR-PnPS (B-cell receptor specific for pneumococcal capsular polysaccharides)

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