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pneumococcal conjugate vaccine 13-GlaxoSmithKline-chickenpox refers to the co-administration of a 13-valent pneumococcal conjugate vaccine (PCV13) and GlaxoSmithKline's investigational live-attenuated varicella vaccine (GSK2761411A). This combination is primarily evaluated in Phase 3 pediatric clinical trials (such as NCT05583331) to assess the safety and immunogenicity of GSK's intramuscular varicella vaccine when given alongside other routine childhood immunizations. The varicella component is a live-attenuated virus (Oka strain) intended to prevent chickenpox (varicella), while the PCV13 component provides protection against 13 serotypes of Streptococcus pneumoniae, the causative agent of pneumonia, meningitis, and bacteremia. The investigational varicella vaccine is specifically designed for intramuscular injection, providing a potential alternative to the traditional subcutaneous route used for marketed varicella vaccines.
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