pneumococcal polysaccharide serotype 6b

Pneumococcal polysaccharide serotype 6b is a monovalent vaccine antigen consisting of the purified capsular polysaccharide derived from *Streptococcus pneumoniae* serotype 6B. Developed and evaluated by the Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), it is designed to elicit a specific immune response to prevent pneumococcal infections caused by this particular serotype. The mechanism of action involves the stimulation of B-lymphocytes to produce serotype-specific antibodies (opsonins). these antibodies facilitate the opsonization, phagocytosis, and subsequent killing of the bacteria by the host's immune system. While serotype 6B is a common component of polyvalent pneumococcal vaccines, this specific entry refers to the research and clinical development efforts focused on the 6B polysaccharide as a standalone entity or specific vaccine candidate at Erasmus MC.

Other names

Pneumococcal polysaccharide type 6BStreptococcus pneumoniae serotype 6B capsular polysaccharidePneumococcal vaccine serotype 6B