pneumococcal polysaccharide serotype 8 conjugated to CRM197 adsorbed on aluminium phosphate

A **monovalent pneumococcal conjugate vaccine component** consisting of *Streptococcus pneumoniae* serotype 8 capsular polysaccharide covalently linked to the carrier protein CRM197 and adsorbed on aluminium phosphate. As a glycoconjugate vaccine antigen, it is designed to convert the poorly immunogenic T-cell-independent serotype 8 polysaccharide into a T-cell-dependent immunogen, promoting serotype-specific anti-capsular antibody responses, immunologic memory, and opsonophagocytic killing of pneumococci expressing serotype 8. This specific antigen is not a standalone marketed product to current public knowledge, but is used as an individual monovalent component within higher-valent investigational or approved multivalent pneumococcal conjugate vaccine formulations developed for prevention of pneumococcal infection. The provided context links it to Rijksinstituut voor Volksgezondheid en Milieu, but the exact serotype-8 monovalent component name itself most commonly appears as a component description rather than as a separately branded drug.

Other names

pneumococcal polysaccharide serotype 8 conjugated to CRM197 adsorbed on aluminium phosphateserotype 8 pneumococcal polysaccharide CRM197 conjugate adsorbed on aluminium phosphateserotype8 pneumococcal polysaccharide CRM197 conjugate adsorbed on aluminium phosphateserotype-8 pneumococcal polysaccharide CRM197 conjugate adsorbed on aluminium phosphatepneumococcal serotype 8 CRM197 conjugate