pneumococcal polysaccharide serotype 9V

Pneumococcal polysaccharide serotype 9V refers to the specific capsular polysaccharide derived from or mimicking the *Streptococcus pneumoniae* serotype 9V. Developed as a vaccine candidate by Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), it aims to provide targeted immunity against pneumococcal infections caused by this specific serotype. The mechanism involves the induction of B-cell responses and the production of serotype-specific antibodies that facilitate opsonophagocytosis of the bacteria. In the context of Erasmus MC's research, this often involves synthetic oligosaccharide structures conjugated to carrier proteins (such as CRM197) to improve immunogenicity in vulnerable populations, including infants and the elderly, who may not respond well to pure polysaccharide antigens.

Other names

Streptococcus pneumoniae serotype 9V capsular polysaccharidepneumococcal serotype 9V vaccine candidate