Drug intelligence / Profile preview

poa compressa pollen

Development stage
Unknown
Lead developer
ALK Abelló
Administration
Percutaneous, Subcutaneous, Intradermal
01

Overview

Poa compressa pollen is a biological allergen extract derived from the pollen of the *Poa compressa* plant, commonly known as Canada bluegrass or flat-stemmed bluegrass. It is primarily utilized as a diagnostic agent in allergenic skin testing (such as skin prick or intradermal tests) to identify individuals with IgE-mediated hypersensitivity to this specific grass species. Additionally, it is used in allergen immunotherapy (AIT), where patients are administered gradually increasing doses of the extract to induce immunological tolerance and reduce symptoms of allergic rhinitis and conjunctivitis. The extract contains a complex mixture of proteins and glycoproteins that act as allergens, specifically cross-linking allergen-specific IgE antibodies bound to high-affinity receptors on mast cells and basophils, thereby triggering the release of inflammatory mediators.

Other names
Canada bluegrass pollenFlat-stemmed blue grass pollenPoa compressa pollen extract
02

Targets

IgE (Immunoglobulin E)TCR (T cell antigen receptor complex)

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