Drug intelligence / Profile preview

Pola Office Plus

Development stage
Unknown
Lead developer
SDI Limited
Modality
Small Molecules
Administration
Topical
01

Overview

Pola Office Plus is a professional, high-concentration in-office dental whitening system developed by SDI Limited. It features a 37.5% hydrogen peroxide gel that is chemically activated, eliminating the need for a bleaching light to achieve results. The mechanism of action involves the release of reactive oxygen radicals that penetrate tooth enamel and dentin to oxidize and break down complex organic chromophores responsible for discoloration. To manage the common side effect of treatment-induced tooth sensitivity, the formulation incorporates potassium nitrate, which acts as a desensitizing agent by preventing the repolarization of sensory nerve fibers within the dental pulp. It is indicated for the rapid whitening of extrinsic and intrinsic tooth stains in a clinical setting.

Brand names
Pola Office Plus
Other names
Pola Office+
02

Targets

Tooth chromophore

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