Drug intelligence / Profile preview

policresulen + cinchocaine

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Topical, Rectal
01

Overview

Faktu is a topical combination medication indicated for the treatment of various anorectal disorders, most notably hemorrhoids, anal fissures, and proctitis. It consists of two active components: policresulen and cinchocaine hydrochloride. Policresulen is a polymolecular organic acid that acts as a local hemostatic and astringent; it selectively coagulates necrotic or pathologically altered tissue while leaving healthy squamous epithelium unaffected, thereby promoting healing and preventing infection. Cinchocaine hydrochloride (also known as dibucaine) is a potent amide-type local anesthetic that provides symptomatic relief from pain, burning, and pruritus by inhibiting the initiation and conduction of nerve impulses through the blockade of voltage-gated sodium channels. The product was originally developed by Altana (later Nycomed and Takeda) and is currently part of the pharma& Group portfolio.

Brand names
Faktu
Other names
policresulen / cinchocaine hydrochloridepolicresulen + cinchocaine hydrochloride
02

Targets

NaV (Voltage-gated sodium channels)CaM (Calmodulin)PS (Phosphatidylserine)

Beyond the preview

Go deeper on policresulen + cinchocaine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on policresulen + cinchocaine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call