Poliflav M.A.

Poliflav M.A. is a multi-ingredient vascular support formulation, typically classified as a dietary supplement or nutraceutical, primarily utilized in the management of chronic venous insufficiency and microcirculatory disorders. Its core composition includes a combination of bioflavonoids: diosmin, troxerutin, and hesperidin. The therapeutic effect is achieved through phlebotonic and vasoprotective actions. Diosmin increases venous tone by inhibiting catechol-O-methyltransferase (COMT), which leads to prolonged activity of norepinephrine on the venous wall. Troxerutin and hesperidin contribute by reducing capillary hyper-permeability and providing anti-inflammatory effects through the inhibition of pro-inflammatory mediators and the expression of adhesion molecules. The product is frequently indicated for conditions such as varicose veins, hemorrhoidal disease, and capillary fragility, and it is largely associated with the Italian pharmaceutical market.

Brand names

Poliflav M.A.

Other names

Poliflav MA