Drug intelligence / Profile preview

poliomyelitis vaccine vero cell inactivated Sabin strains

Development stage
Unknown
Lead developer
Sinovac Biotech
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**Poliomyelitis Vaccine Vero Cell Inactivated Sabin Strains** is Sinovac's single-dose, ready-to-use trivalent Sabin-strain inactivated poliovirus vaccine. Each 0.5 mL vial contains formaldehyde-inactivated poliovirus types 1, 2, and 3 propagated in Vero cells, providing active immunization against poliomyelitis in infants from 2 months of age and children. The vaccine induces antibodies to all three poliovirus serotypes and is administered by intramuscular injection. This exact single-dose presentation was used as the active control comparator for Sinovac's five-dose multidose sIPV presentation trial; it contains no preservative, including no 2-phenoxyethanol. Sinovac received Chinese NMPA registration approval on July 12, 2021, and WHO prequalification became effective on June 6, 2022. ([extranet.who.int](https://extranet.who.int/prequal/sites/default/files/vwa_vaccine/pq_375__sIPV_1dose_Sinovac_PI-2022.pdf))

Other names
sIPVsingle-dose sIPVsingle-person sIPV control vaccineSabin strain inactivated poliovirus vaccine
02

Targets

Poliovirus type 2 capsid proteinSabin poliovirus type 3 capsid antigens

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