Poliprotect

Poliprotect is a 100% natural synergistic molecular complex used as a mucosal protective agent, primarily for the relief of heartburn, epigastric pain, burning, gastroesophageal reflux disease (GERD), and functional dyspepsia[1][2][4][5]. It is not a pharmaceutical drug but a substance-based medical device composed of a polysaccharide fraction (from Aloe vera, Malva sylvestris, and Althaea officinalis), minerals (limestone and nahcolite), and a flavonoid fraction from Glycyrrhiza glabra and Matricaria recutita[1][5]. Its primary mechanism is the formation of a mucoadhesive, protective film that mimics physiological mucus to shield the gastroesophageal and gastric mucosa from aggressive factors like acid and bile, thus reducing irritation and mucosal damage[2][4]. The flavonoid fraction provides antioxidant protection, further reducing mucosal irritation[4]. Poliprotect is marketed in Europe as NeoBianacid. Clinical evidence, including randomized controlled trials, demonstrates that it is non-inferior to proton pump inhibitors like omeprazole for symptom relief in non-erosive reflux and functional heartburn, with an excellent safety profile and good tolerability in adults, children, pregnant, and breastfeeding women[1][3][5]. It does not alter the gut microbiota and can be used alone or in combination with anti-secretory drugs[5].

Brand names

Poliprotect

Other names

NeoBianacid