Pollinex Tyrosine

**Pollinex Tyrosine** is a brand name for a series of allergy vaccines from Allergy Therapeutics, featuring glutaraldehyde-modified pollen allergens (such as grass, rye, tree, or ragweed extracts) adsorbed onto **L-tyrosine** as a depot adjuvant for subcutaneous immunotherapy. Developed for pre-seasonal treatment of IgE-mediated seasonal allergic rhinitis, it induces immune tolerance by shifting the Th2-biased response toward a balanced Th1/Th2 profile, elevating allergen-specific **IgG blocking antibodies** (especially IgG4), suppressing IgE, and reducing basophil mediator release like histamine. Administered in short courses (e.g., 4 injections for Pollinex Quattro variants), it enhances tolerability and efficacy compared to traditional immunotherapy, primarily in patients unresponsive to antihistamines.[1][2][7][9]

Brand names

Pollinex Tyrosine

Other names

Pollinex