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Polvac Grass+Rye
- Development stage
- Unknown
- Lead developer
- University of Zurich
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intralymphatic
01
Overview
Polvac Grass+Rye is an allergen extract suspension containing grass and rye pollen allergens adsorbed onto a microcrystalline tyrosine (MCT) adjuvant. Developed by the University of Zurich, it is designed for intralymphatic immunotherapy (ILIT) to treat allergic rhinitis and allergic asthma. The treatment protocol involves three ultrasound-guided injections into the inguinal lymph nodes over a 4-8 week period. This approach aims to induce immune tolerance more efficiently than traditional subcutaneous immunotherapy by delivering the allergens directly to the secondary lymphoid organs, potentially reducing the number of required doses and the overall duration of treatment.
- Brand names
- Polvac Grass+Rye
- Other names
- Polvac ILIT
02
Targets
Phleum pratense allergensLol p (Perennial ryegrass pollen allergen)
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