Drug intelligence / Profile preview

poly-l-lysine G2 + vitamin c

Development stage
Preclinical
Modality
Small Molecules, Peptides, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Poly-l-lysine G2 + vitamin C is a combination of a second-generation dendrigraft of poly-L-lysine (DGL2) and vitamin C (ascorbic acid), primarily developed for dermocosmetic and topical dermatological applications. Poly-L-lysine G2 acts as a biocompatible, biodegradable polymer that stabilizes and enhances the delivery of vitamin C to the skin. Vitamin C is well known for its antioxidant properties, stimulation of collagen synthesis, tissue repair, and regulation of inflammatory processes. The combination improves the stability and liposolubility of vitamin C—overcoming its inherent instability in cosmetic formulations—and increases its transcutaneous penetration. This results in enhanced moisturization, protection against oxidative stress, improved skin barrier function, reduced inflammation and pruritus (itching), as well as better tolerance with less irritation compared to standalone vitamin C products[1][3][7]. Clinical studies have shown significant improvements in atopic dermatitis symptoms with this combination[1]. Poly-L-lysine-based vectors are obtained via green chemistry methods.

Other names
poly-L-lysine dendrigraft generation 2 + ascorbic acidDGL2 + vitamin C
02

Targets

Cell surface and extracellular matrix negatively charged components

Beyond the preview

Go deeper on poly-l-lysine G2 + vitamin c.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on poly-l-lysine G2 + vitamin c.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call