polyacrylamide hydrogel + silver ions

**Polyacrylamide hydrogel + silver ions** is a **composite wound dressing** material consisting of a synthetic polymer hydrogel matrix—polyacrylamide (PAA)—incorporated or loaded with silver ions, most commonly in the form of silver nanoparticles (AgNPs). The hydrogel acts as a moist wound interface and carrier for the controlled, localized delivery of silver ions, which provide broad-spectrum antibacterial activity. The mechanism of action combines the hydrogel's ability to maintain a suitable wound-healing environment with the antimicrobial effects of silver, which disrupts bacterial cell membranes, interacts with bacterial DNA, and generates reactive oxygen species. This formulation has shown efficacy against both standard and antibiotic-resistant bacteria, reduced wound size, and promoted healing in preclinical studies and limited clinical testing for chronic ulcers and wound infections[1][3][5].

Other names

polyacrylamide hydrogel with silverPAA hydrogel with silver ionspolyacrylamide-silver hydrogel