Drug intelligence / Profile preview

polyacrylate polyalcohol copolymer

Development stage
Phase 4
Lead developer
Promedon
Administration
Implant
01

Overview

Vantris is a biocompatible, synthetic, non-absorbable tissue-bulking agent composed of polyacrylate polyalcohol copolymer (PPC) particles suspended in a glycerol and physiological saline carrier. It is designed for the endoscopic treatment of vesicoureteral reflux (VUR) in children. When injected subureterally (using the STING or HIT techniques) at the ureterovesical junction, Vantris increases the tissue volume, correcting the anatomy of the distal ureter valve and preventing the retrograde flow of urine toward the kidneys. Because it is non-biodegradable, Vantris provides a stable, permanent bulk that resists degradation and migration, offering long-term efficacy in resolving VUR.

Brand names
VantrisVantris VUR
Other names
PPCPPCHpolyacrylate polyalcohol copolymerpolyacrylate polyalcohol copolymer hydrogelpolyacrylate-polyalcohol copolymer

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