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polyethylene glycol
- Development stage
- Approved
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Oral, Topical, Parenteral, Intravenous, Intramuscular, Subcutaneous, Ophthalmic, Rectal
01
Overview
**Polyethylene glycol** is a family of inert, water-soluble polyether polymers whose clinical properties depend substantially on molecular weight and formulation. High-molecular-weight oral preparations, particularly polyethylene glycol 3350, act as **osmotic laxatives**: they remain largely unabsorbed in the gastrointestinal tract and retain water in the bowel lumen, softening stool and promoting bowel movements. Polyethylene glycol is also used in bowel-cleansing preparations, typically with electrolytes, and can serve as a lubricant or vehicle in ophthalmic formulations. The unqualified term is not chemically specific because it can refer to PEG materials with different average molecular weights and clinical uses.
- Brand names
- MiraLAXRestoraLAXMoviPrepClearLaxGaviLAXHealthyLaxNatura-LaxLaxidoMovicol
- Other names
- poly(ethylene glycol)PEGmacrogol
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