polyethylene glycol + ascorbic acid + simethicone

This is a combination drug consisting of polyethylene glycol (PEG), ascorbic acid (vitamin C), and simethicone. It is primarily used for bowel preparation before colonoscopy. Polyethylene glycol acts as an osmotic laxative by retaining water in the stool, resulting in softer stools and promoting bowel movements. Ascorbic acid enhances the laxative effect through its osmotic properties and also helps reduce the required volume of PEG solution. Simethicone is an antifoaming agent that reduces gas bubbles in the gastrointestinal tract, improving mucosal visibility during colonoscopy and reducing patient discomfort such as bloating or abdominal fullness[1][2][3][4]. The combination has been shown to provide superior bowel cleansing efficacy compared to PEG-ascorbic acid alone, with better patient tolerability and improved endoscopist satisfaction[1][2].

Other names

PEG-Asc plus simethiconePEG-Asc + simethiconepolyethylene glycol with ascorbic acid and simethicone