Drug intelligence / Profile preview

polyethylene glycol + sodium sulfate + sodium chloride + potassium chloride + sodium bicarbonate

Development stage
Unknown
Lead developer
Braintree
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Oral
01

Overview

Polyethylene glycol + sodium sulfate + sodium chloride + potassium chloride + sodium bicarbonate is a compound osmotic laxative formulation primarily used for bowel cleansing prior to colonoscopy, barium enema X-ray examination, or surgical procedures, and for the treatment of functional constipation. The product, widely known in China under the brand name **Shutaiqing**, consists of polyethylene glycol (PEG) 4000 (or 3350 in some formulations) and a balanced mixture of electrolytes. PEG acts as an osmotic agent that retains water in the intestinal lumen, increasing stool volume and stimulating peristalsis. Sodium sulfate provides additional osmotic pressure to facilitate bowel evacuation. The inclusion of electrolytes (sodium chloride, potassium chloride, and sodium bicarbonate) is critical to maintaining the body's isosmotic balance during the induced diarrhea, thereby minimizing the risk of clinically significant fluid or electrolyte shifts. A similar formulation was previously marketed in the United States under the brand name **Suclear**.

Brand names
Shutaiqing舒泰清Suclear
Other names
Compound Sodium Sulfate and Polyethylene Glycol Powder复方硫酸钠聚乙二醇散PEG-4000 with electrolytesPEG4000 with electrolytesPEG 4000 with electrolytesPEG-3350 with electrolytesPEG3350 with electrolytesPEG 3350 with electrolytes

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