Drug intelligence / Profile preview

polyethylene glycol electrolyte solution

Development stage
Unknown
Lead developer
Shandong University
Modality
Small Molecules
Administration
Oral
01

Overview

Polyethylene glycol electrolyte solution (PEG-ELS) is an osmotic laxative used for bowel cleansing prior to colonoscopy or surgery. It works by creating an osmotic effect in the intestinal lumen, which retains water and increases stool volume, thereby stimulating peristalsis and evacuating the bowel. The inclusion of electrolytes (sodium chloride, sodium bicarbonate, potassium chloride, and often sodium sulfate) helps maintain electrolyte balance and prevent significant fluid shifts during the large-volume lavage. In the context of research at **Shandong University**, PEG-ELS is being evaluated in various regimens—including standard 2L, high-volume 4L, and low-volume 2L combined with bisacodyl—to determine the optimal preparation for patients with a history of colorectal resection.

Brand names
GoLYTELYColyteNuLYTELYTriLyteGavilyte
Other names
polyethylene glycol 3350 and electrolytesPEG-3350 with electrolytesPEG3350 with electrolytesPEG 3350 with electrolytes

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