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Polyethylene glycol electrolyte solution (PEG-ELS) is an osmotic laxative used for bowel cleansing prior to colonoscopy or surgery. It works by creating an osmotic effect in the intestinal lumen, which retains water and increases stool volume, thereby stimulating peristalsis and evacuating the bowel. The inclusion of electrolytes (sodium chloride, sodium bicarbonate, potassium chloride, and often sodium sulfate) helps maintain electrolyte balance and prevent significant fluid shifts during the large-volume lavage. In the context of research at **Shandong University**, PEG-ELS is being evaluated in various regimens—including standard 2L, high-volume 4L, and low-volume 2L combined with bisacodyl—to determine the optimal preparation for patients with a history of colorectal resection.
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