Drug intelligence / Profile preview

polyethylene glycol loxenatide

Development stage
Phase 4
Lead developer
Hansoh Pharmaceutical Group
Modality
Peptides
Administration
Subcutaneous
01

Overview

Polyethylene glycol loxenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily for the treatment of type 2 diabetes mellitus. It is derived from exendin-4 and modified with polyethylene glycol (PEG) to enhance its pharmacokinetic properties. This modification increases its half-life and reduces immunogenicity, allowing for once-weekly administration. It is also being explored for its potential effects on weight management and cardiovascular outcomes.

Brand names
Peganlin
Other names
PEG loxenatidePEG-LoxenatidePolyethylene glycol (PEG) loxenatideFulaimei
02

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