Drug intelligence / Profile preview

Polyphetamine

Development stage
Discontinued
Lead developer
ITL Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Polyphetamine was a proprietary multi-salt amphetamine product developed by ITL Pharmaceuticals for the treatment of Attention Deficit/Hyperactivity Disorder (ADHD). As a central nervous system stimulant, it was designed to modulate the levels of key neurotransmitters involved in focus and impulse control. The mechanism of action involves the release and reuptake inhibition of dopamine and norepinephrine through interactions with the dopamine transporter (DAT), norepinephrine transporter (NET), and trace amine-associated receptor 1 (TAAR1). The project was in the IND-enabling phase around 2011, but development has since been discontinued following the cessation of ITL Pharmaceuticals' operations.

Brand names
Polyphetamine
02

Targets

DAT (Dopamine plasma membrane transport protein)VMAT2 (Vesicular monoamine transporter 2)NET (Norepinephrine Transporter)TAAR1 (Trace amine-associated receptor 1)

Beyond the preview

Go deeper on Polyphetamine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Polyphetamine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call