Polysaccharide superparamagnetic iron oxide

Polysaccharide superparamagnetic iron oxide refers to nanoparticles composed of an iron oxide core exhibiting superparamagnetism and coated with a natural or synthetic polysaccharide layer. These particles are engineered for biomedical applications such as drug delivery, magnetic resonance imaging (MRI) contrast enhancement, and targeted therapy. The polysaccharide coating improves biocompatibility, stability in biological fluids, and allows for further functionalization with drugs or targeting ligands. Mechanistically, these nanoparticles can be directed by external magnetic fields to specific tissues or tumors for localized drug delivery or imaging. They are also being explored as carriers for nucleic acids like mRNA in gene therapy research[1][2][3][4][5][6][8].

Other names

Polysaccharide-coated superparamagnetic iron oxidePolysaccharide-covered superparamagnetic iron oxide colloidSPIONs