polyvalent anti-snake venom serum

Polyvalent anti-snake venom serum (also known as polyvalent snake antivenom) is a life-saving therapeutic preparation of equine immunoglobulins (typically F(ab')2 fragments or whole IgG) purified from the plasma of healthy horses immunized against the venoms of multiple medically important venomous snake species. It is primarily indicated for the treatment of snakebite envenomation. The serum works by physically binding to and neutralizing the active toxic components of circulating snake venoms, such as phospholipases A2, metalloproteinases, serine proteases, and neurotoxins, thereby preventing or reversing systemic and local envenomation symptoms (including coagulopathy, hemorrhage, and neurotoxicity). Various formulations are manufactured globally by developers such as Premium Serums and Vaccines, Bharat Serums and Vaccines, Vins Bioproducts, and Serum Institute of India, with regional specificities tailored to local snake populations (e.g., the 'Big Four' venomous snakes of India: Indian Cobra, Common Krait, Russell's Viper, and Saw-scaled Viper, or sub-Saharan African species).

Brand names

NORAF-PremiumPANAF-Premium

Other names

polyvalent anti-snake venom serapolyvalent snake antivenompolyvalent snake venom antiserumsnake venom antiserumsnake venom antiserum polyvalent