Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
polyvinyl alcohol microspheres
- Development stage
- Unknown
- Lead developer
- Boston Scientific
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Intra-arterial
01
Overview
Polyvinyl alcohol (PVA) microspheres are permanent embolic agents used in interventional oncology, specifically for transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) and other hypervascular tumors. These microspheres are engineered from polyvinyl alcohol, a biocompatible and non-absorbable polymer, to provide mechanical occlusion of the tumor's blood supply. This occlusion induces local ischemia and tumor necrosis while potentially increasing the local concentration of co-administered chemotherapeutic drugs. A specific product mentioned in clinical literature is 8spheres, developed by Jiangsu Hengrui Pharmaceutical, which features microspheres in the 100–300 μm size range. Unlike temporary agents like gelatin sponges, PVA microspheres provide a more permanent vascular blockage, though they may be associated with higher transient elevations in liver enzymes due to the completeness of the embolization.
- Brand names
- 8spheres
- Other names
- PVA microspheresblank PVA microspheres8SM
Beyond the preview
Go deeper on polyvinyl alcohol microspheres.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on polyvinyl alcohol microspheres.