polyvinylpyrrolidone-coated silver nanoparticles

Polyvinylpyrrolidone-coated silver nanoparticles are **silver nanoparticles stabilized with polyvinylpyrrolidone (PVP)**, a synthetic polymer. The PVP coating increases colloidal stability, prevents aggregation, and modifies biological interactions, making these nanoparticles suitable for **biomedical applications** such as wound care, drug delivery, and antimicrobial coatings. Their mechanism of action primarily involves the gradual release of silver ions from the nanoparticle surface, which exert **broad-spectrum antimicrobial effects** by disrupting bacterial membranes, interfering with respiration and cellular enzymes, and inducing oxidative stress, DNA damage, and cell death. PVP-AgNPs are also used in cancer therapy research for targeted delivery and cytotoxicity against tumor cells. The PVP coating is primarily functional and does not independently contribute to therapeutic activity but enhances nanoparticle properties such as dispersion and biocompatibility[1][2][3].

Other names

polyvinylpyrrolidone-coated AgNPsPVP-AgNPspolyvinylpyrrolidone stabilized silver nanoparticles