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pomegranate peel extract gel

Development stage: Preclinical
Lead developer: Cairo University
Administration: Topical

Overview

Pomegranate peel extract gel is a botanical therapeutic formulation being investigated as an adjunctive treatment for Stage II-III periodontitis. Administered subgingivally following scaling and root planing (SRP), the gel leverages the bioactive compounds found in pomegranate (*Punica granatum*) peels, such as punicalagin and ellagic acid, which possess potent antioxidant, anti-inflammatory, and antimicrobial properties. The extract is hypothesized to improve periodontal healing by reducing inflammation and inhibiting tissue-degrading enzymes like matrix metalloproteinase-8 (MMP-8).

Other names: pomegranate peel extract

Targets

MMP8 (Neutrophil collagenase)

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