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populus deltoides pollen
- Development stage
- Unknown
- Lead developer
- ALK Abelló
- Modality
- Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intradermal, Percutaneous, Subcutaneous, Sublingual
01
Overview
Populus deltoides pollen is an allergenic extract derived from the pollen of the Eastern Cottonwood tree (Populus deltoides). It is a biologic product used for both diagnosing and treating allergies to this specific pollen. For diagnosis, it is used in skin tests to confirm sensitivity. As a treatment, it is administered via subcutaneous injection as a form of allergy immunotherapy, also known as hyposensitization. The therapy involves repeated injections of the extract to gradually desensitize the patient's immune system, reducing the allergic reaction to cottonwood pollen. This process works by modulating the immune system's response, shifting it away from an allergic IgE-mediated response. The product is marketed by companies like ALK-Abello, Inc. as a non-standardized allergenic extract. [1, 3, 14]
- Other names
- Eastern Cottonwood PollenCottonwood Eastern Common
02
Targets
FCER1 (Fc epsilon RI receptor)IgE (Immunoglobulin E)
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