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PopVax Strep A vaccine
- Development stage
- Preclinical
- Lead developer
- PopVax
- Modality
- mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
01
Overview
PopVax Strep A vaccine is an investigational mRNA-encoded virus-like particle (VLP) vaccine designed to prevent infections caused by *Streptococcus pyogenes* (Group A Streptococcus). Developed using PopVax's proprietary mRNA platform, the vaccine delivers mRNA that instructs host cells to produce VLPs displaying Strep A-specific antigens. This approach aims to mimic the structural presentation of the pathogen to elicit a robust and protective immune response, potentially addressing a wide range of Strep A-related conditions, from pharyngitis to more severe invasive diseases. As of early 2024, the program is in the design phase, with Phase 1 clinical trials projected to begin in 2028.
- Other names
- Strep A VaccineGroup A Streptococcus vaccine
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