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porcine greater omentum extract
- Development stage
- Preclinical
- Lead developer
- Gyeongsang National University
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Intraperitoneal
01
Overview
Porcine greater omentum extract (pGOEs) is an aqueous extract derived from the greater omentum of domestic pigs [4230]. It is enriched with various growth factors, including hepatocyte growth factor (HGF), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and insulin-like growth factor 1 (IGF-1), as well as antioxidant proteins such as superoxide dismutase, peroxiredoxin, and hemopexin [4230]. Developed by researchers at Gyeongsang National University, pGOEs has demonstrated therapeutic potential for liver regeneration and the treatment of liver injuries by promoting hepatocyte proliferation and stimulating cell cycle progression [4230].
- Other names
- aqueous porcine greater omentum-extractporcine greater omentum-extracts
02
Targets
EGFR (Epidermal growth factor receptor)MET (Mesenchymal-epithelial transition factor receptor)IGF-1R (Insulin-like growth factor 1 receptor)PDGFR (PDGFR family)VEGFR (VEGFR family)
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