Drug intelligence / Profile preview

porcine thyroid

Development stage
Unknown
Lead developer
AbbVie
Administration
Oral
01

Overview

Porcine thyroid is a **natural desiccated thyroid hormone replacement therapy** prepared from the dried thyroid glands of pigs. It contains the endogenous thyroid hormones **levothyroxine** and **liothyronine** in a fixed animal-derived mixture and is used primarily for **hypothyroidism**, with additional historical and labeled use in **euthyroid goiter** and **thyroid cancer management**. After oral administration, T4 is converted peripherally to T3, and T3 binds nuclear thyroid hormone receptors to regulate gene transcription controlling metabolic rate, growth, and development. The product is an older biologic hormone preparation rather than a synthetic single-entity drug, and marketed examples include Armour Thyroid and NP Thyroid.

Brand names
Armour ThyroidNP ThyroidNature-ThroidWesthroid
Other names
thyroid porcinedesiccated thyroidnatural desiccated thyroidthyroid extractdesiccated thyroid extract
02

Targets

THRA (Thyroid hormone receptor alpha)THRB (Thyroid hormone receptor beta)

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