Drug intelligence / Profile preview

Positrin

Development stage
Unknown
Lead developer
Industria Químico Farmacéutica Sigma
Modality
Small Molecules
Administration
Oral
01

Overview

Positrin is a macrolide antibiotic containing erythromycin ethylsuccinate as its active ingredient. It is primarily used to treat a wide range of bacterial infections, including upper and lower respiratory tract infections caused by sensitive strains of *Streptococci*, *Staphylococci*, *Pneumococci*, *Haemophilus influenzae*, *Bordetella pertussis*, and *Corynebacterium diphtheriae*. Additionally, it is indicated for genitourinary infections caused by *Chlamydia*, *Staphylococcus aureus*, and *Treponema pallidum*. Positrin serves as an effective alternative for patients with penicillin allergies. The drug exerts its antibacterial effect by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby inhibiting RNA-dependent protein synthesis. It is marketed by Sigmacorp in Bolivia and is available in both coated tablet and oral suspension formulations.

Brand names
Positrin
Other names
erythromycin ethylsuccinate
02

Targets

Bacterial 50S ribosomal subunit

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