Drug intelligence / Profile preview

Postoperative Formula No. 1

Development stage
Unknown
Modality
Peptides, Small Molecules
Administration
Oral
01

Overview

Postoperative Formula No. 1 is a traditional Chinese medicine (TCM) decoction primarily used in the management of postoperative recovery, particularly following abdominal or gastrointestinal surgeries. The formula is designed to promote the recovery of gastrointestinal motility and alleviate symptoms such as postoperative ileus, abdominal distension, and pain. While specific compositions can vary by hospital or practitioner, it typically includes herbs known for their prokinetic and anti-inflammatory properties, such as *Magnolia officinalis* (Houpo), *Aurantii Fructus Immaturus* (Zhishi), and *Radix Aucklandiae* (Mu Xiang). The mechanism of action involves the modulation of gastrointestinal hormones (such as motilin and gastrin) and the reduction of inflammatory cytokines that contribute to intestinal paralysis after surgical trauma.

Other names
Shuhou No. 1Postoperative Formula 1
02

Targets

CCK2R (Cholecystokinin 2 Receptor)MLNR (Human motilin receptor)

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