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Potassium acetate is an approved small molecule drug used primarily as a source of potassium to prevent or treat hypokalemia (low blood potassium levels), especially in patients who cannot take oral medications. It is typically administered intravenously and may be added to large volume IV fluids. Potassium, the principal intracellular cation, plays a critical role in maintaining fluid and electrolyte balance, as well as supporting the function of kidneys, heart, muscles, and the nervous system. The acetate component serves as an alternative source of bicarbonate via metabolic conversion in the liver[1][2][4]. Potassium acetate is also used when specific intravenous fluid formulations are required that cannot be met by standard solutions[1].
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