Drug intelligence / Profile preview

potassium chloride + sodium chloride

Development stage
Unknown
Lead developer
Eli Lilly
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

Potassium chloride + sodium chloride is a combination electrolyte replacement therapy containing essential cations and anions for the maintenance of fluid and electrolyte balance. Available in both oral supplement and intravenous injection forms, it is primarily used to treat or prevent potassium and sodium deficiencies. The intravenous solution is indicated for parenteral fluid and electrolyte replenishment, while oral formulations are often used as dietary supplements to alleviate tiredness, muscle cramps, and heat prostration resulting from excessive perspiration. As small molecule electrolytes, these components are critical for normal nerve conduction, muscle contraction, heart rhythm, and renal function. The intravenous formulation is a sterile, nonpyrogenic solution providing potassium (K+) and sodium (Na+) ions, requiring careful monitoring to prevent electrolyte imbalances such as hyperkalemia.

Brand names
ThermotabsPotassium Chloride in Sodium Chloride Injection
Other names
KCl + NaClPotassium Chloride and Sodium ChlorideSodium Chloride and Potassium Chloride
02

Targets

KCC2 (Potassium-chloride cotransporter 2)KCNT1 (Potassium channel subfamily T member 1)

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