Drug intelligence / Profile preview

potassium chloride + sodium gluconate + magnesium chloride + sodium acetate + sodium chloride

Development stage
Unknown
Lead developer
B. Braun
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

potassium chloride + sodium gluconate + magnesium chloride + sodium acetate + sodium chloride is a balanced intravenous crystalloid combination product used for parenteral fluid and electrolyte replacement. It contains sodium, potassium, magnesium, chloride, acetate, and gluconate in concentrations designed to approximate plasma electrolyte composition and support restoration or maintenance of extracellular fluid volume. Its pharmacologic effect is not mediated through a discrete receptor target; rather, it replenishes body water and essential electrolytes, while acetate and gluconate are metabolized to bicarbonate precursors that can help buffer metabolic acidosis. The product is used in settings such as dehydration, hypovolemia, perioperative care, trauma, and critical illness, and is marketed in branded presentations including Normosol-R, Plasma-Lyte A, and Isolyte S.

Brand names
Normosol-RPlasma-Lyte AIsolyte S
Other names
multiple electrolytes injectionmulti-electrolyte intravenous solutionbalanced electrolyte solutionparenteral fluid and electrolyte replenisher

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