Drug intelligence / Profile preview

potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrose monohydrate

Development stage
Approved
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

**Potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrose monohydrate** is a fixed-combination intravenous crystalloid and carbohydrate solution marketed as formulations such as **Lactated Ringer's and Dextrose** and **Potassium Chloride in Lactated Ringer's and 5% Dextrose Injection**. It is a parenteral small-molecule and inorganic salt combination used as a source of water, electrolytes, and calories, and as an alkalinizing agent. Pharmacologically, it replenishes extracellular sodium, potassium, calcium, and chloride, provides lactate that is metabolized to bicarbonate and can help buffer metabolic acidosis, and supplies dextrose as a source of carbohydrate calories. It is used in adults and pediatric patients for fluid and electrolyte replacement, treatment or prevention of dehydration and electrolyte depletion, and support in conditions requiring alkalinization or minimal caloric supplementation. Publicly identified manufacturers and label holders include Pfizer and ICU Medical.

Brand names
Lactated Ringer's and DextrosePotassium Chloride in Lactated Ringer's and 5% Dextrose Injection
Other names
potassium chloride + sodium lactate + sodium chloride + calcium chloride + dextrose monohydratelactated ringer's and dextrosepotassium chloride in lactated ringer's and dextrosepotassium chloride in lactated ringer's and 5% dextrose injectionlactated ringer's and dextrose injectionpotassium chloride in lactated ringer's and dextrose injectionpotassium chloride in lactated ringer's and dextrose injection usp

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