potassium oxybate

Potassium oxybate is the potassium salt form of oxybate, the active moiety gamma-hydroxybutyrate, a **small-molecule central nervous system depressant** used as one component of mixed-oxybate pharmaceutical products. Clinically, potassium oxybate is not generally marketed as a standalone product; instead, it is one of the four oxybate salts in Jazz Pharmaceuticals' lower-sodium fixed-dose combination product Xywav, which is approved for cataplexy or excessive daytime sleepiness in narcolepsy and for idiopathic hypersomnia. Its therapeutic activity is attributed to oxybate pharmacology, with effects thought to involve **GABA-B receptor agonism** and downstream modulation of noradrenergic, dopaminergic, and thalamocortical neuronal activity.

Other names

potassium oxybatepotassium gamma-hydroxybutyratepotassium 4-hydroxybutyratepotassium4-hydroxybutyratepotassium-4-hydroxybutyrate